Speckle-Type POZ Protein (SPOP-B) Peptide
SPOP-B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
-
- Target See all SPOP-B products
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Peptide Type
- Synthetic
- Origin
- Mammalian
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YHASDVLETS GWKSMVVSHP HLVAEAYRSL ASAQCPFLGP PRKRLKQS
- Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of SPOP antibody,
Alternative Names: SPOP control peptide, SPOP antibody Blocking Peptide, Anti-SPOP Blocking Peptide, speckle-type POZ protein Blocking Peptide, TEF2 Blocking Peptide
-
-
- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
-
- Target
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Background
- SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes.
- Molecular Weight
- 42 kDa
-
You are here:
