Speckle-Type POZ Protein (SPOP-B) Peptide
SPOP-B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936081
Quick Overview for Speckle-Type POZ Protein (SPOP-B) Peptide (ABIN936081)
Target
SPOP-B
(Speckle-Type POZ Protein (SPOP-B))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YHASDVLETS GWKSMVVSHP HLVAEAYRSL ASAQCPFLGP PRKRLKQS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SPOP antibody,
Alternative Names: SPOP control peptide, SPOP antibody Blocking Peptide, Anti-SPOP Blocking Peptide, speckle-type POZ protein Blocking Peptide, TEF2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Background
- SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes.
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Molecular Weight
- 42 kDa
Target
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