Lysocardiolipin Acyltransferase 1 (LCLAT1) Peptide
LCLAT1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936156
Quick Overview for Lysocardiolipin Acyltransferase 1 (LCLAT1) Peptide (ABIN936156)
Target
LCLAT1
(Lysocardiolipin Acyltransferase 1 (LCLAT1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of LYCAT antibody,
Alternative Names: LYCAT control peptide, LYCAT antibody Blocking Peptide, Anti-LYCAT Blocking Peptide, Lysocardiolipin Acyltransferase Blocking Peptide, ALCAT1 Blocking Peptide, FLJ37965 Blocking Peptide, UNQ1849 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
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Background
- LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognises both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
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Molecular Weight
- 44 kDa
Target
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