Tribbles Pseudokinase 2 (TRIB2) Peptide
Quick Overview for Tribbles Pseudokinase 2 (TRIB2) Peptide (ABIN936167)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- YPFHDIEPSS LFSKIRRGQF NIPETLSPKA KCLIRSILRR EPSERLTSQE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TRIB2 antibody,
Alternative Names: TRIB2 control peptide, TRIB2 antibody Blocking Peptide, Anti-TRIB2 Blocking Peptide, Tribbles Homolog 2 Blocking Peptide, GS3955 Blocking Peptide, TRB2 Blocking Peptide, TRIB2, TRIB-2, TRIB 2, TRIB-2 Blocking Peptide, TRIB 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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Background
- TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
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Molecular Weight
- 39 kDa
Target
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