Tribbles Pseudokinase 2 (TRIB2) (Middle Region) Peptide
TRIB2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRIB2 products
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIB2 antibody (Catalog #: ARP55377_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Synonyms
- TRIB2 Peptide, Trb2 Peptide, Xtrbl Peptide, gs3955 Peptide, c5fw Peptide, trb2 Peptide, xtrb2 Peptide, TRB2 Peptide, C5FW Peptide, GS3955 Peptide, TRB-2 Peptide, AW319517 Peptide, RGD1564451 Peptide, tribbles pseudokinase 2 Peptide, tribbles pseudokinase 2 S homeolog Peptide, TRIB2 Peptide, trib2 Peptide, trib2.S Peptide, Trib2 Peptide
- Background
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TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Alias Symbols: GS3955, TRB2, C5FW
Protein Interaction Partner: UBQLN4
Protein Size: 343 - Molecular Weight
- 39 kDa
- Gene ID
- 28951
- NCBI Accession
- NM_021643, NP_067675
- UniProt
- Q92519
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