Adrenergic, alpha-1B-, Receptor (ADRA1B) Peptide
ADRA1B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
-
- Target See all ADRA1B products
- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
- Peptide Type
- Synthetic
- Origin
- Mammalian
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP
- Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of ADRA1 B antibody,
Alternative Names: ADRA1B control peptide, ADRA1B antibody Blocking Peptide, Anti-ADRA1B Blocking Peptide, adrenergic, alpha-1B-, receptor Blocking Peptide, ADRA1 Blocking Peptide, ALPHA1BAR Blocking Peptide, ADRA1B, ADRAB-1, ADRAB 1, ADRAB-1 Blocking Peptide, ADRAB 1 Blocking Peptide
-
-
- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
-
- Target
- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
- Background
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
- Molecular Weight
- 57 kDa
-
You are here:
