Renin (REN) Peptide
REN
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936227
Quick Overview for Renin (REN) Peptide (ABIN936227)
Target
Renin (REN)
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YSSKKLCTLA IHAMDIPPPT GPTWALGATF IRKFYTEFDR RNNRIGFALA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of REN antibody,
Alternative Names: Renin control peptide, Renin antibody Blocking Peptide, Anti-Renin Blocking Peptide, FLJ10761 Blocking Peptide, REN Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Renin (REN)
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Background
- Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.
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Molecular Weight
- 45 kDa
Target
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