Peroxisomal Biogenesis Factor 19 (PEX19) Peptide
PEX19
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936282
Quick Overview for Peroxisomal Biogenesis Factor 19 (PEX19) Peptide (ABIN936282)
Target
PEX19
(Peroxisomal Biogenesis Factor 19 (PEX19))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PEX19 antibody,
Alternative Names: PEX19 control peptide, PEX19 antibody Blocking Peptide, Anti-PEX19 Blocking Peptide, peroxisomal biogenesis factor 19 Blocking Peptide, D1S2223E Blocking Peptide, FLJ55296 Blocking Peptide, HK33 Blocking Peptide, PMP1 Blocking Peptide, PMPI Blocking Peptide, PXF Blocking Peptide, PXMP1 Blocking Peptide, PEX19, PEX-19, PEX 19, PEX-19 Blocking Peptide, PEX 19 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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Background
- This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 33 kDa
Target
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