Glucosidase, Beta, Acid (GBA) Peptide
GBA
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936300
Quick Overview for Glucosidase, Beta, Acid (GBA) Peptide (ABIN936300)
Target
GBA
(Glucosidase, Beta, Acid (GBA))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GBA antibody,
Alternative Names: GBA control peptide, GBA antibody Blocking Peptide, Anti-GBA Blocking Peptide, glucosidase, beta, acid Blocking Peptide, GBA1 Blocking Peptide, GCB Blocking Peptide, GLUC Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GBA (Glucosidase, Beta, Acid (GBA))
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Background
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 59 kDa
Target
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