Vacuolar Protein Sorting 4 Homolog B (vps4b) Peptide
vps4b
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all VPS4B (vps4b) products
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of VPS4 B antibody,
Alternative Names: VPS4B control peptide, VPS4B antibody Blocking Peptide, Anti-VPS4B Blocking Peptide, vacuolar protein sorting 4 homolog B, S. cerevisiae Blocking Peptide, MIG1 Blocking Peptide, SKD1 Blocking Peptide, SKD1B Blocking Peptide, VPS4-2 Blocking Peptide, VPS4B, VPSB-4, VPSB 4, VPSB-4 Blocking Peptide, VPSB 4 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Background
- The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of AA sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
- Molecular Weight
- 49 kDa
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