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Vacuolar Protein Sorting 4 Homolog B (vps4b) Peptide

vps4b Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936304

Quick Overview for Vacuolar Protein Sorting 4 Homolog B (vps4b) Peptide (ABIN936304)

Target

VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Origin

Mammalian

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of VPS4 B antibody,
    Alternative Names: VPS4B control peptide, VPS4B antibody Blocking Peptide, Anti-VPS4B Blocking Peptide, vacuolar protein sorting 4 homolog B, S. cerevisiae Blocking Peptide, MIG1 Blocking Peptide, SKD1 Blocking Peptide, SKD1B Blocking Peptide, VPS4-2 Blocking Peptide, VPS4B, VPSB-4, VPSB 4, VPSB-4 Blocking Peptide, VPSB 4 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

    Background

    The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of AA sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.

    Molecular Weight

    49 kDa
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