Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) Peptide
UBE2V1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936320
Quick Overview for Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) Peptide (ABIN936320)
Target
UBE2V1
(Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GVVDPRAISV LAKWQNSYSI KVVLQELRRL MMSKENMKLP QPPEGQCYSN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of UBE2 V1 antibody,
Alternative Names: UBE2V1 control peptide, UBE2V1 antibody Blocking Peptide, Anti-UBE2V1 Blocking Peptide, ubiquitin-conjugating enzyme E2 variant 1 Blocking Peptide, CIR1 Blocking Peptide, CROC-1 Blocking Peptide, CROC1 Blocking Peptide, UBE2V Blocking Peptide, UEV-1 Blocking Peptide, UEV1 Blocking Peptide, UEV1A Blocking Peptide, UBE2V1, UBEV1-2, UBEV1 2, UBEV1-2 Blocking Peptide, UBEV1 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Background
- Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
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Molecular Weight
- 16 kDa
Target
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