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Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (Middle Region) Peptide

UBE2V1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5673384
  • Target See all UBE2V1 products
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    IYENRIYSLK IECGPKYPEA PPFVRFVTKI NMNGVNSSNG VVDPRAISVL
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- UBE2V1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    Synonyms
    CIR1 Peptide, CROC-1 Peptide, CROC1 Peptide, UBE2V Peptide, UEV-1 Peptide, UEV1 Peptide, UEV1A Peptide, 0610011J09Rik Peptide, AI256840 Peptide, D7Bwg1382e Peptide, CROC-1B Peptide, ubiquitin conjugating enzyme E2 V1 Peptide, ubiquitin-conjugating enzyme E2 variant 1 Peptide, UBE2V1 Peptide, ube2v1 Peptide, Ube2v1 Peptide
    Background
    Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

    Alias Symbols: CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1

    Protein Size: 221
    Gene ID
    7335
    NCBI Accession
    NM_001032288, NP_001027459
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