Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide
Quick Overview for Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide (ABIN936841)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- AQRLQAQLNE LQAQLSQKEQ AAEHYKLQME KAKTHYDAKK QQNQELQEQL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NUMA1 antibody,
Alternative Names: NUMA1 control peptide, NUMA1 antibody Blocking Peptide, Anti-NUMA1 Blocking Peptide, nuclear mitotic apparatus protein 1 Blocking Peptide, NUMA Blocking Peptide, NUMA1, NUMA-1, NUMA 1, NUMA-1 Blocking Peptide, NUMA 1 Blocking Peptide -
Purification
- Immunoaffinity chromatography
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Background
- NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
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Molecular Weight
- 238 kDa
Target
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