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Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide

NUMA1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936841

Quick Overview for Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide (ABIN936841)

Target

NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Origin

Mammalian

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    AQRLQAQLNE LQAQLSQKEQ AAEHYKLQME KAKTHYDAKK QQNQELQEQL

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of NUMA1 antibody,
    Alternative Names: NUMA1 control peptide, NUMA1 antibody Blocking Peptide, Anti-NUMA1 Blocking Peptide, nuclear mitotic apparatus protein 1 Blocking Peptide, NUMA Blocking Peptide, NUMA1, NUMA-1, NUMA 1, NUMA-1 Blocking Peptide, NUMA 1 Blocking Peptide

    Purification

    Immunoaffinity chromatography
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

    Background

    NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.

    Molecular Weight

    238 kDa
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