Ureidopropionase, beta (UPB1) Peptide
Quick Overview for Ureidopropionase, beta (UPB1) Peptide (ABIN937005)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- AVVISNSGAV LGKTRKNHIP RVGDFNESTY YMEGNLGHPV FQTQFGRIAV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of UPB1 antibody,
Alternative Names: UPB1 control peptide, UPB1 antibody Blocking Peptide, Anti-UPB1 Blocking Peptide, Ureidopropionase Beta Blocking Peptide, BUP1 Blocking Peptide, UPB1, UPB-1, UPB 1, UPB-1 Blocking Peptide, UPB 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- UPB1 (Ureidopropionase, beta (UPB1))
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Background
- UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
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Molecular Weight
- 42 kDa
Target
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