NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptide
NKIRAS1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937066
Quick Overview for NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptide (ABIN937066)
Target
NKIRAS1
(NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of NKIRAS1 antibody,
Alternative Names: NKIRAS1 control peptide, NKIRAS1 antibody Blocking Peptide, Anti-NKIRAS1 Blocking Peptide, Nfkb Inhibitor Interacting Ras-Like 1 Blocking Peptide, KBRAS1 Blocking Peptide, kappaB-Ras1 Blocking Peptide, NKIRAS1, NKIRAS-1, NKIRAS 1, NKIRAS-1 Blocking Peptide, NKIRAS 1 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
-
Background
- NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
-
Molecular Weight
- 22 kDa
Target
-
You are here:
