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Methyl-CpG Binding Domain Protein 1 (MBD1) Peptide

MBD1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937113

Quick Overview for Methyl-CpG Binding Domain Protein 1 (MBD1) Peptide (ABIN937113)

Target

MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

Origin

Mammalian

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    CKVWETEDTV EPTSTSWNPR GWPGTHVSLS PPPASMMWVS CRRSWCPSSQ

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of MBD1 antibody,
    Alternative Names: MBD1 control peptide, MBD1 antibody Blocking Peptide, Anti-MBD1 Blocking Peptide, Methyl-Cpg Binding Domain Protein 1 Blocking Peptide, CXXC3 Blocking Peptide, PCM1 Blocking Peptide, RFT Blocking Peptide, MBD1, MBD-1, MBD 1, MBD-1 Blocking Peptide, MBD 1 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

    Background

    MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus.

    Molecular Weight

    65 kDa
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