N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) Peptide
NAT2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937133
Quick Overview for N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) Peptide (ABIN937133)
Target
NAT2
(N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NAT2 antibody,
Alternative Names: NAT2 control peptide, NAT2 antibody Blocking Peptide, Anti-NAT2 Blocking Peptide, N-Acetyltransferase 2 Blocking Peptide, Arylamine N-Acetyltransferase Blocking Peptide, AAC2 Blocking Peptide, NAT2, NAT-2, NAT 2, NAT-2 Blocking Peptide, NAT 2 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
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Background
- NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.
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Molecular Weight
- 32 kDa
Target
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