Inhibin, beta A (INHBA) Peptide
INHBA
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937158
Quick Overview for Inhibin, beta A (INHBA) Peptide (ABIN937158)
Target
INHBA
(Inhibin, beta A (INHBA))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of INHBA antibody,
Alternative Names: INHBA control peptide, INHBA antibody Blocking Peptide, Anti-INHBA Blocking Peptide, inhibin, beta A Blocking Peptide, EDF Blocking Peptide, FRP Blocking Peptide -
Purification
- higher than 95 percent by SDS-PAGE
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- INHBA (Inhibin, beta A (INHBA))
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Background
- The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
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Molecular Weight
- 44 kDa
Target
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