DNA Methyltransferase 1-Associated Protein 1 (DMAP1) Peptide
Quick Overview for DNA Methyltransferase 1-Associated Protein 1 (DMAP1) Peptide (ABIN937253)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- DAWTKAETDH LFDLSRRFDL RFVVIHDRYD HQQFKKRSVE DLKERYYHIC
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DMAP1 antibody,
Alternative Names: DMAP1 control peptide, DMAP1 antibody Blocking Peptide, Anti-DMAP1 Blocking Peptide, DNA methyltransferase 1 associated protein 1 Blocking Peptide, DMAP1, DMAP-1, DMAP 1, DMAP-1 Blocking Peptide, DMAP 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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Background
- DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication.
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Molecular Weight
- 51 kDa
Target
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