2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Peptide
OAS2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937298
Quick Overview for 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Peptide (ABIN937298)
Target
OAS2
(2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DEMVNTICDV LQEPEQFPLV QGVAIGGSYG RKTVLRGNSD GTLVLFFSDL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of OAS2 antibody,
Alternative Names: OAS2 control peptide, OAS2 antibody Blocking Peptide, Anti-OAS2 Blocking Peptide, 2'-5'-Oligoadenylate Synthetase 2 69/71Kda Blocking Peptide, MGC78578 Blocking Peptide, OAS2, OAS-2, OAS 2, OAS-2 Blocking Peptide, OAS 2 Blocking Peptide -
Purification
- Protein G affinity purified immunoglobulin
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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Background
- OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.
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Molecular Weight
- 79 kDa
Target
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