Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) Peptide
RMI1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937339
Quick Overview for Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) Peptide (ABIN937339)
Target
RMI1
(Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DGILEIPKGE LNGFYALQIN SLVDVSQPAY SQIQKLRGKN TTNDLVTAEA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RMI1 antibody,
Alternative Names: RMI1 control peptide, RMI1 antibody Blocking Peptide, Anti-RMI1 Blocking Peptide, Rmi1 Recq Mediated Genome Instability 1 Homolog Blocking Peptide, BLAP75 Blocking Peptide, C9orf76 Blocking Peptide, FLJ12888 Blocking Peptide, RP.1 Blocking Peptide, RMI1, RMI-1, RMI 1, RMI-1 Blocking Peptide, RMI 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
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Background
- RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.
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Molecular Weight
- 70 kDa
Target
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