Erythropoietin Receptor (EPOR) Peptide
EPOR
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937364
Quick Overview for Erythropoietin Receptor (EPOR) Peptide (ABIN937364)
Target
EPOR
(Erythropoietin Receptor (EPOR))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of EPOR antibody,
Alternative Names: EPOr control peptide, EPOr antibody Blocking Peptide, Anti-EPOr Blocking Peptide, Erythropoietin Receptor Blocking Peptide, MGC138358 Blocking Peptide -
Purification
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- EPOR (Erythropoietin Receptor (EPOR))
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Background
- The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
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Molecular Weight
- 53 kDa
Target
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