Erythropoietin Receptor (EPOR) (N-Term) Peptide
-
- Target See all EPOR products
- EPOR (Erythropoietin Receptor (EPOR))
- Protein Region
- N-Term
- Origin
- Mouse
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SVRFWCSLPT ADTSSFVPLE LQVTEASGSP RYHRIIHINE VVLLDAPAGL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Epor Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Synonyms
- EPOR Peptide, epor Peptide, EPO-R Peptide, erythropoietin receptor Peptide, erythropoietin receptor L homeolog Peptide, EPOR Peptide, epor Peptide, Epor Peptide, epor.L Peptide
- Background
-
Epor is a receptor for erythropoietin. Epor mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, Epor can also activate STAT1 and STAT3. Epor may also activate the LYN tyrosine kinase.
Alias Symbols: -
Protein Interaction Partner: Crkl,Jak2,Kit,Lyn,Lyn,Pik3r1,Ptpn1,Stat5a,Stat5b
Protein Size: 507 - Molecular Weight
- 55 kDa
- Gene ID
- 13857
- NCBI Accession
- NM_010149, NP_034279
- UniProt
- P14753
-