Heart and Neural Crest Derivatives Expressed 2 (HAND2) Peptide
HAND2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937519
Quick Overview for Heart and Neural Crest Derivatives Expressed 2 (HAND2) Peptide (ABIN937519)
Target
HAND2
(Heart and Neural Crest Derivatives Expressed 2 (HAND2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Hand2 antibody,
Alternative Names: Hand2 control peptide, Hand2 antibody Blocking Peptide, Anti-Hand2 Blocking Peptide, heart and neural crest derivatives expressed transcript 2 Blocking Peptide, AI225906 Blocking Peptide, AI661148 Blocking Peptide, Ehand2 Blocking Peptide, Hed Blocking Peptide, Th2 Blocking Peptide, Thing2 Blocking Peptide, bHLHa26 Blocking Peptide, dHAND Blocking Peptide, Hand2, Hand-2, Hand 2, Hand-2 Blocking Peptide, Hand 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
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Background
- Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
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Molecular Weight
- 24 kDa
Target
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