Insulin-Like Growth Factor 1 Receptor (IGF1R) Peptide
Quick Overview for Insulin-Like Growth Factor 1 Receptor (IGF1R) Peptide (ABIN937530)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- DRHSGHKAEN GPGPGVLVLR ASFDERQPYA HMNGGRKNER ALPLPQSSTC
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IGF1 R antibody,
Alternative Names: IGF1R control peptide, IGF1R antibody Blocking Peptide, Anti-IGF1R Blocking Peptide, insulin-like growth factor 1 receptor Blocking Peptide, CD221 Blocking Peptide, IGFIR Blocking Peptide, JTK13 Blocking Peptide, MGC142170 Blocking Peptide, MGC142172 Blocking Peptide, MGC18216 Blocking Peptide, IGF1R, IGFR-1, IGFR 1, IGFR-1 Blocking Peptide, IGFR 1 Blocking Peptide -
Purification
- Immunoaffinity chromatography
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Background
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
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Molecular Weight
- 71 kDa
Target
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