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HLA Class I alpha F (HLAF) Peptide

HLAF Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937647

Quick Overview for HLA Class I alpha F (HLAF) Peptide (ABIN937647)

Target

HLA-F (HLAF) (HLA Class I alpha F (HLAF))

Origin

Mammalian

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    EAGSHTLQGM NGCDMGPDGR LLRGYHQHAY DGKDYISLNE DLRSWTAADT

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-F antibody,
    Alternative Names: HLA-F control peptide, HLA-F antibody Blocking Peptide, Anti-HLA-F Blocking Peptide, Major Histocompatibility Complex Class I F Blocking Peptide, CDA12 Blocking Peptide, HLA-5.4 Blocking Peptide, HLA-CDA12 Blocking Peptide, HLAF Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    HLA-F (HLAF) (HLA Class I alpha F (HLAF))

    Background

    HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.

    Molecular Weight

    48 kDa
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