Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) Peptide
MTHFD2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937673
Quick Overview for Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) Peptide (ABIN937673)
Target
MTHFD2
(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EAVVISGRKL AQQIKQEVRQ EVEEWVASGN KRPHLSVILV GENPASHSYV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MTHFD2 antibody,
Alternative Names: MTHFD2 control peptide, MTHFD2 antibody Blocking Peptide, Anti-MTHFD2 Blocking Peptide, Methylenetetrahydrofolate Dehydrogenase Blocking Peptide, Nadp+ Dependent 2 Methenyltetrahydrofolate Cyclohydrolase Blocking Peptide, NMDMC Blocking Peptide, MTHFD2, MTHFD-2, MTHFD 2, MTHFD-2 Blocking Peptide, MTHFD 2 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
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Background
- MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.
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Molecular Weight
- 35 kDa
Target
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