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Deltex Homolog 2 (DTX2) Peptide

DTX2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937691
  • Target See all DTX2 products
    DTX2 (Deltex Homolog 2 (DTX2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP DNAQGRKVLE
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of DTX2 antibody,
    Alternative Names: DTX2 control peptide, DTX2 antibody Blocking Peptide, Anti-DTX2 Blocking Peptide, Deltex Homolog 2 Blocking Peptide, KIAA1528 Blocking Peptide, MGC71098 Blocking Peptide, RNF58 Blocking Peptide, DTX2, DTX-2, DTX 2, DTX-2 Blocking Peptide, DTX 2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    DTX2 (Deltex Homolog 2 (DTX2))
    Background
    DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
    Molecular Weight
    62 kDa
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