Deltex Homolog 2 (DTX2) Peptide
DTX2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937691
Quick Overview for Deltex Homolog 2 (DTX2) Peptide (ABIN937691)
Target
DTX2
(Deltex Homolog 2 (DTX2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP DNAQGRKVLE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DTX2 antibody,
Alternative Names: DTX2 control peptide, DTX2 antibody Blocking Peptide, Anti-DTX2 Blocking Peptide, Deltex Homolog 2 Blocking Peptide, KIAA1528 Blocking Peptide, MGC71098 Blocking Peptide, RNF58 Blocking Peptide, DTX2, DTX-2, DTX 2, DTX-2 Blocking Peptide, DTX 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- DTX2 (Deltex Homolog 2 (DTX2))
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Background
- DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
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Molecular Weight
- 62 kDa
Target
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