Karyopherin (Importin) beta 1 (KPNB1) Peptide
KPNB1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937840
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Karyopherin (Importin) beta 1 (KPNB1) Peptide (ABIN937840)
Target
KPNB1
(Karyopherin (Importin) beta 1 (KPNB1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KPNB1 antibody,
Alternative Names: KPNB1 control peptide, KPNB1 antibody Blocking Peptide, Anti-KPNB1 Blocking Peptide, karyopherin, importin beta 1 Blocking Peptide, IMB1 Blocking Peptide, IPO1 Blocking Peptide, IPOB Blocking Peptide, Impnb Blocking Peptide, MGC2155 Blocking Peptide, MGC2156 Blocking Peptide, MGC2157 Blocking Peptide, NTF97 Blocking Peptide, KPNB1, KPNB-1, KPNB 1, KPNB-1 Blocking Peptide, KPNB 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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Background
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
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Molecular Weight
- 96 kDa
Target
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