Poly-U Binding Splicing Factor 60KDa (PUF60) Peptide
PUF60
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN937860
Quick Overview for Poly-U Binding Splicing Factor 60KDa (PUF60) Peptide (ABIN937860)
Target
PUF60
(Poly-U Binding Splicing Factor 60KDa (PUF60))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- EIIVKIFVEF SIASETHKAI QALNGRWFAG RKVVAEVYDQ ERFDNSDLSA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PUF60 antibody,
Alternative Names: PUF60 control peptide, PUF60 antibody Blocking Peptide, Anti-PUF60 Blocking Peptide, Poly-U Binding Splicing Factor 60Kda Blocking Peptide, FIR Blocking Peptide, FLJ31379 Blocking Peptide, RoBPI Blocking Peptide, SIAHBP1 Blocking Peptide, PUF60, PUF-60, PUF 60, PUF-60 Blocking Peptide, PUF 60 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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Background
- PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.
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Molecular Weight
- 58 kDa
Target
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