Periplakin (PPL) Peptide
PPL
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all PPL products
- PPL (Periplakin (PPL))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PPL antibody,
Alternative Names: Periplakin control peptide, Periplakin antibody Blocking Peptide, Anti-Periplakin Blocking Peptide, KIAA0568 Blocking Peptide, MGC134872 Blocking Peptide, PPL Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- PPL (Periplakin (PPL))
- Background
- PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
- Molecular Weight
- 205 kDa
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