Neuronal Pentraxin II (NPTX2) Peptide
Quick Overview for Neuronal Pentraxin II (NPTX2) Peptide (ABIN937923)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- ELEDEKSLLH NETSAHRQKT ESTLNALLQR VTELERGNSA FKSPDAFKVS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NPTX2 antibody,
Alternative Names: NPTX2 control peptide, NPTX2 antibody Blocking Peptide, Anti-NPTX2 Blocking Peptide, neuronal pentraxin II Blocking Peptide, NARP Blocking Peptide, NP-II Blocking Peptide, NP2 Blocking Peptide, NPTX2, NPTX-2, NPTX 2, NPTX-2 Blocking Peptide, NPTX 2 Blocking Peptide -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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Background
- This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
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Molecular Weight
- 47 kDa
Target
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