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Neuronal Pentraxin II (NPTX2) Peptide

NPTX2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937923

Quick Overview for Neuronal Pentraxin II (NPTX2) Peptide (ABIN937923)

Target

NPTX2 (Neuronal Pentraxin II (NPTX2))

Origin

Mammalian

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    ELEDEKSLLH NETSAHRQKT ESTLNALLQR VTELERGNSA FKSPDAFKVS

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of NPTX2 antibody,
    Alternative Names: NPTX2 control peptide, NPTX2 antibody Blocking Peptide, Anti-NPTX2 Blocking Peptide, neuronal pentraxin II Blocking Peptide, NARP Blocking Peptide, NP-II Blocking Peptide, NP2 Blocking Peptide, NPTX2, NPTX-2, NPTX 2, NPTX-2 Blocking Peptide, NPTX 2 Blocking Peptide

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    NPTX2 (Neuronal Pentraxin II (NPTX2))

    Background

    This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.

    Molecular Weight

    47 kDa
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