Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) Peptide
EIF3E
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937943
Quick Overview for Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) Peptide (ABIN937943)
Target
EIF3E
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ELLQGKLDLL SDTNMVDFAM DVYKNLYSDD IPHALREKRT TVVAQLKQLQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of EIF3 E antibody,
Alternative Names: EIF3E control peptide, EIF3E antibody Blocking Peptide, Anti-EIF3E Blocking Peptide, Eukaryotic Translation Initiation Factor 3 Subunit E Blocking Peptide, EIF3-P48 Blocking Peptide, EIF3S6 Blocking Peptide, INT6 Blocking Peptide, eIF3-p46 Blocking Peptide, EIF3E, EIFE-3, EIFE 3, EIFE-3 Blocking Peptide, EIFE 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Background
- EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
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Molecular Weight
- 52 kDa
Target
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