Tetratricopeptide Repeat Domain 8 (TTC8) Peptide
TTC8
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937985
Quick Overview for Tetratricopeptide Repeat Domain 8 (TTC8) Peptide (ABIN937985)
Target
TTC8
(Tetratricopeptide Repeat Domain 8 (TTC8))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TTC8 antibody,
Alternative Names: TTC8 control peptide, TTC8 antibody Blocking Peptide, Anti-TTC8 Blocking Peptide, Tetratricopeptide Repeat Domain 8 Blocking Peptide, BBS8 Blocking Peptide, TTC8, TTC-8, TTC 8, TTC-8 Blocking Peptide, TTC 8 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
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Background
- The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
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Molecular Weight
- 54 kDa
Target
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