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Muscleblind-Like 2 (MBNL2) Peptide

MBNL2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937993
  • Target See all MBNL2 products
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of MBNL2 antibody,
    Alternative Names: MBNL2 control peptide, MBNL2 antibody Blocking Peptide, Anti-MBNL2 Blocking Peptide, muscleblind-like 2, Drosophila Blocking Peptide, DKFZp781H1296 Blocking Peptide, MBLL Blocking Peptide, MBLL39 Blocking Peptide, MGC120625 Blocking Peptide, MGC120626 Blocking Peptide, MGC120628 Blocking Peptide, PRO2032 Blocking Peptide, MBNL2, MBNL-2, MBNL 2, MBNL-2 Blocking Peptide, MBNL 2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Background
    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
    Molecular Weight
    28 kDa
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