Muscleblind-Like 2 (MBNL2) Peptide
MBNL2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937993
Quick Overview for Muscleblind-Like 2 (MBNL2) Peptide (ABIN937993)
Target
MBNL2
(Muscleblind-Like 2 (MBNL2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MBNL2 antibody,
Alternative Names: MBNL2 control peptide, MBNL2 antibody Blocking Peptide, Anti-MBNL2 Blocking Peptide, muscleblind-like 2, Drosophila Blocking Peptide, DKFZp781H1296 Blocking Peptide, MBLL Blocking Peptide, MBLL39 Blocking Peptide, MGC120625 Blocking Peptide, MGC120626 Blocking Peptide, MGC120628 Blocking Peptide, PRO2032 Blocking Peptide, MBNL2, MBNL-2, MBNL 2, MBNL-2 Blocking Peptide, MBNL 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MBNL2 (Muscleblind-Like 2 (MBNL2))
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Background
- MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
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Molecular Weight
- 28 kDa
Target
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