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Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptide

SF3B1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938085

Quick Overview for Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptide (ABIN938085)

Target

SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Origin

Mammalian

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    ERLDPFADGG KTPDPKMNAR TYMDVMREQH LTKEEREIRQ QLAEKAKAGE

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of SF3 B1 antibody,
    Alternative Names: SF3B1 control peptide, SF3B1 antibody Blocking Peptide, Anti-SF3B1 Blocking Peptide, Splicing Factor 3B Subunit 1 155Kda Blocking Peptide, SF3B1, SFB1-3, SFB1 3, SFB1-3 Blocking Peptide, SFB1 3 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    Background

    SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.

    Molecular Weight

    87 kDa
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