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Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide

SHB Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938096
  • Target See all SHB products
    SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ERPSQPPQAV PQASSAASAS CGPATASCFS ASSGSLPDDS GSTSDLIRAY
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody,
    Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP11-3J10.8 Blocking Peptide, bA3J10.2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
    Background
    SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
    Molecular Weight
    55 kDa
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