Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide
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- Target See all SHB products
- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ERPSQPPQAV PQASSAASAS CGPATASCFS ASSGSLPDDS GSTSDLIRAY
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody,
Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP11-3J10.8 Blocking Peptide, bA3J10.2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
- Background
- SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
- Molecular Weight
- 55 kDa
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