Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide
SHB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938096
Quick Overview for Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide (ABIN938096)
Target
SHB
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ERPSQPPQAV PQASSAASAS CGPATASCFS ASSGSLPDDS GSTSDLIRAY
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody,
Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP.8 Blocking Peptide, bA3J10.2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
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Background
- SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
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Molecular Weight
- 55 kDa
Target
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