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Centromere Protein H (CENPH) Peptide

CENPH Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938137

Quick Overview for Centromere Protein H (CENPH) Peptide (ABIN938137)

Target

CENPH (Centromere Protein H (CENPH))

Origin

Mammalian

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    ESWDLEEKLL DIRKKRLQLK QASESKLLEI QTEKNKQKID LDSMENSERI

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of CENPH antibody,
    Alternative Names: CENPH control peptide, CENPH antibody Blocking Peptide, Anti-CENPH Blocking Peptide, Centromere Protein H Blocking Peptide, NNF1 Blocking Peptide, PMF1 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    CENPH (Centromere Protein H (CENPH))

    Background

    Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

    Molecular Weight

    27 kDa
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