Centromere Protein H (CENPH) Peptide
Quick Overview for Centromere Protein H (CENPH) Peptide (ABIN938137)
Target
Origin
Source
Application
-
-
Peptide Type
- Synthetic
-
Sequence
- ESWDLEEKLL DIRKKRLQLK QASESKLLEI QTEKNKQKID LDSMENSERI
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of CENPH antibody,
Alternative Names: CENPH control peptide, CENPH antibody Blocking Peptide, Anti-CENPH Blocking Peptide, Centromere Protein H Blocking Peptide, NNF1 Blocking Peptide, PMF1 Blocking Peptide
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- CENPH (Centromere Protein H (CENPH))
-
Background
- Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
-
Molecular Weight
- 27 kDa
Target
-