Sepiapterin Reductase (SPR) Peptide
SPR
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938157
Quick Overview for Sepiapterin Reductase (SPR) Peptide (ABIN938157)
Target
SPR
(Sepiapterin Reductase (SPR))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SPR antibody,
Alternative Names: SPR control peptide, SPR antibody Blocking Peptide, Anti-SPR Blocking Peptide, sepiapterin reductase, 7,8-dihydrobiopterin:NADP+ oxidoreductase Blocking Peptide, SDR38C1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SPR (Sepiapterin Reductase (SPR))
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Background
- This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
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Molecular Weight
- 28 kDa
Target
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