Histidine-Rich Glycoprotein (HRG) Peptide
HRG
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938186
Quick Overview for Histidine-Rich Glycoprotein (HRG) Peptide (ABIN938186)
Target
HRG
(Histidine-Rich Glycoprotein (HRG))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EVLPLPEANF PSFPLPHHKH PLKPDNQPFP QSVSESCPGK FKSGFPQVSM
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of HRG antibody,
Alternative Names: HRG control peptide, HRG antibody Blocking Peptide, Anti-HRG Blocking Peptide, Histidine-Rich Glycoprotein Blocking Peptide, DKFZp779H1622 Blocking Peptide, HPRG Blocking Peptide, HRGP Blocking Peptide -
Purification
- Immunoaffinity purification
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- HRG (Histidine-Rich Glycoprotein (HRG))
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Background
- This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
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Molecular Weight
- 58 kDa
Target
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