Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Peptide
GADD45B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938237
Quick Overview for Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Peptide (ABIN938237)
Target
GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GADD45 B antibody,
Alternative Names: GADD45B control peptide, GADD45B antibody Blocking Peptide, Anti-GADD45B Blocking Peptide, Growth Arrest And Dna-Damage-Inducible Beta Blocking Peptide, DKFZP566B133 Blocking Peptide, GADD45BETA Blocking Peptide, MYD118 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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Background
- GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
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Molecular Weight
- 18 kDa
Target
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