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Myelin Basic Protein (MBP) Peptide

MBP Reactivity: Mammalian Host: Synthetic WB, BP, IHC
Catalog No. ABIN938289

Quick Overview for Myelin Basic Protein (MBP) Peptide (ABIN938289)

Target

MBP (Myelin Basic Protein (MBP))

Origin

Mammalian

Source

  • 6
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    FGGDRGAPKR GSGKDSHHPA RTAHYGSLPQ KSHGRTQDEN PVVHFFKNIV

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of MBP antibody,
    Alternative Names: MBP control peptide, MBP antibody Blocking Peptide, Anti-MBP Blocking Peptide, Myelin Basic Protein Blocking Peptide, MGC99675 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    MBP (Myelin Basic Protein (MBP))

    Background

    The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.

    Molecular Weight

    33 kDa
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