Myelin Basic Protein (MBP) Peptide
Quick Overview for Myelin Basic Protein (MBP) Peptide (ABIN938289)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- FGGDRGAPKR GSGKDSHHPA RTAHYGSLPQ KSHGRTQDEN PVVHFFKNIV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MBP antibody,
Alternative Names: MBP control peptide, MBP antibody Blocking Peptide, Anti-MBP Blocking Peptide, Myelin Basic Protein Blocking Peptide, MGC99675 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MBP (Myelin Basic Protein (MBP))
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Background
- The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
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Molecular Weight
- 33 kDa
Target
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