NOP2/Sun Domain Family, Member 2 (NSUN2) Peptide
NSUN2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938320
Quick Overview for NOP2/Sun Domain Family, Member 2 (NSUN2) Peptide (ABIN938320)
Target
NSUN2
(NOP2/Sun Domain Family, Member 2 (NSUN2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FINSRIITVS MEDVKILLTQ ENPFFRKLSS ETYSQAKDLA KGSIVLKYEP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NSUN2 antibody,
Alternative Names: NSUN2 control peptide, NSUN2 antibody Blocking Peptide, Anti-NSUN2 Blocking Peptide, Nol1/Nop2/Sun Domain Family Member 2 Blocking Peptide, FLJ20303 Blocking Peptide, MISU Blocking Peptide, SAKI Blocking Peptide, TRM4 Blocking Peptide, NSUN2, NSUN-2, NSUN 2, NSUN-2 Blocking Peptide, NSUN 2 Blocking Peptide -
Purification
- Immunoaffinity chromatography
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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Background
- Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA).
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Molecular Weight
- 86 kDa
Target
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