Deoxynucleotidyltransferase, terminal (DNTT) Peptide
DNTT
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938414
Quick Overview for Deoxynucleotidyltransferase, terminal (DNTT) Peptide (ABIN938414)
Target
TdT (DNTT)
(Deoxynucleotidyltransferase, terminal (DNTT))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DNTT antibody,
Alternative Names: DNTT control peptide, DNTT antibody Blocking Peptide, Anti-DNTT Blocking Peptide, Deoxynucleotidyltransferase Terminal Blocking Peptide, TDT Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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Background
- DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor geneegments.
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Molecular Weight
- 58 kDa
Target
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