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Vanin 2 (VNN2) Peptide

VNN2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938432

Quick Overview for Vanin 2 (VNN2) Peptide (ABIN938432)

Target

VNN2 (Vanin 2 (VNN2))

Origin

Mammalian

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    FRGFISRDGF NFTELFENAG NLTVCQKELC CHLSYRMLQK EENEVYVLGA

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of VNN2 antibody,
    Alternative Names: VNN2 control peptide, VNN2 antibody Blocking Peptide, Anti-VNN2 Blocking Peptide, vanin 2 Blocking Peptide, FOAP-4 Blocking Peptide, GPI-80 Blocking Peptide, VNN2, VNN-2, VNN 2, VNN-2 Blocking Peptide, VNN 2 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    VNN2 (Vanin 2 (VNN2))

    Background

    This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Molecular Weight

    57 kDa
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