DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptide
DDX21
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938433
Quick Overview for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptide (ABIN938433)
Target
DDX21
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FRGQRDGNRR FRGQREGSRG PRGQRSGGGN KSNRSQNKGQ KRSFSKAFGQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DDX21 antibody,
Alternative Names: DDX21 control peptide, DDX21 antibody Blocking Peptide, Anti-DDX21 Blocking Peptide, Dead Blocking Peptide, Asp-Glu-Ala-Asp Box Polypeptide 21 Blocking Peptide, DDX21, DDX-21, DDX 21, DDX-21 Blocking Peptide, DDX 21 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
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Background
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognised by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
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Molecular Weight
- 86 kDa
Target
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