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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptide

SIAH1 Reactivity: Mammalian Host: Synthetic BP, IHC, WB
Catalog No. ABIN938472
  • Target See all SIAH1 products
    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    FTCLPAARTR KRKEMSRQTA TALPTGTSKC PPSQRVPALT GTTASNNDLA
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of SIAH1 antibody,
    Alternative Names: SIAH1 control peptide, SIAH1 antibody Blocking Peptide, Anti-SIAH1 Blocking Peptide, seven in absentia homolog 1, Drosophila Blocking Peptide, SIAH1, SIAH-1, SIAH 1, SIAH-1 Blocking Peptide, SIAH 1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
    Background
    SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
    Molecular Weight
    35 kDa
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